Call For Proposals

Call for Research Grant Proposals: Advancing Medulloblastoma Research


Funding Organizations: The CURE Collaborative (Charities United for Research Excellence)

Bibi Fund, Morgan Adams Foundation, Solving Kids’ Cancer, Ty Louis Foundation


Grant Title: CURE-MB: 2026 Medulloblastoma Breakthrough Catalyst Grants

Letter of Intent (LOI) Deadline: March 1, 2026
Full Proposal Deadline for Invited LOIs: May 1, 2026

Grant Amount: Up to $150,000 per award

Number of Awards: 2


Overview

The CURE Collaborative (Charities United for Research Excellence) invites Letters of Intent for bold, high-risk, high-reward projects that can rapidly advance understanding and treatment of medulloblastoma. We encourage a wide spectrum of proposals that will improve outcomes for medulloblastoma, including those designed to generate pilot/seed data that will position investigators/teams for larger external funding.


Scope of Funding

We welcome proposals that include (but are not limited to):

  • Biology & mechanisms: molecular, genetic, and epigenetic drivers of medulloblastoma pathogenesis.
  • Therapeutic innovation: novel targeted agents, immunotherapies, and approaches to personalization/precision medicine.
  • Translational impact: studies that bridge laboratory discoveries to clear clinical application pathways.


Eligibility Criteria

  • Researchers worldwide affiliated with accredited academic institutions, hospitals, or research organizations.
  • Multidisciplinary and collaborative projects are encouraged.
  • Investigators at all stages of their career are eligible to apply.
  • Preliminary data is not a pre-requisite.
  • Clinical trials are not eligible for funding.
  • Investigators may submit more than one LOI.


Application Process

Interested applicants must submit:

  1. Letter of Intent (max 1 page): objectives/aims, brief methodology, expected outcomes, and a concise innovation paragraph (Times New Roman, 11pt, 1” margins). An additional page of pertinent references is permitted.  Please include a separate cover page with proposal title and name of investigator and submit as a single PDF file with the document file labelled with the principal investigator name. LOI should be submitted to grants@solvingkidscancer.org by 11:59 pm ET March 1, 2026
  2. Following LOI review, selected applicants will be invited to submit a full proposal by May 1, 2026.


Evaluation Criteria

Proposals will be evaluated based on the following:

  • Scientific merit and originality/innovation
  • Feasibility and methodological rigor
  • Investigator qualifications and track record
  • Relevance to medulloblastoma

Potential impact, including but not limited to the likelihood of leveraging larger funding opportunities


Funding and Reporting Requirements

  • Up to $150,000 total per award, disbursed over 2 years (milestones in 2026 and 2027).
  • Progress and financial reports are required prior to the second-year milestone and at project completion.
  • Successful projects may be considered for renewal or supplemental funding based on results.
  • No indirect costs or PI (principal investigator) salary are permitted.


Submission and Contact Information

  • LOIs must be submitted electronically to grants@solvingkidscancer.org by March 1, 2026.
  • Invited full proposals are due May 1, 2026.
  • For questions, contact Donna Ludwinski at donna@solvingkidscancer.org




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